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Prolonged Hypoxia Increases ROS Signaling and RhoA Activation in Pulmonary Artery Smooth Muscle and Endothelial Cells

Phase I of the hypoxic pulmonary vasoconstriction (HPV) response begins upon transition to hypoxia and involves an increase in cytosolic calcium ([Ca(2+)](i)). Phase II develops during prolonged hypoxia and involves increases in constriction without further increases in [Ca(2+)](i), suggesting an in...

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Bibliografische gegevens
Hoofdauteurs: Chi, Annie Y., Waypa, Gregory B., Mungai, Paul T., Schumacker, Paul T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861537/
https://ncbi.nlm.nih.gov/pubmed/19747063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2861
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