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Linkage Analysis of a Cluster-Based Quantitative Phenotype Constructed from Pulmonary Function Test Data in 27 Multigenerational Families with Multiple Asthmatic Members

OBJECTIVE: To identify genes involved in phenotypes that increase one's risk for developing asthma, a complex disease that is likely genetically heterogeneous. Unlike other approaches to locus discovery in the presence of heterogeneity, this method seeks loci that segregate in all or most ascer...

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Detalhes bibliográficos
Main Authors: Reilly, Cavan, Miller, Michael B., Liu, Yuhong, Oetting, William S., King, Richard, Blumenthal, Malcolm
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861531/
https://ncbi.nlm.nih.gov/pubmed/17476113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000101992
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