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Wnt/β-catenin signaling: components, mechanisms, and diseases
Signaling by the Wnt family of secreted glycolipoproteins via the transcription co-activator β-catenin controls embryonic development and adult homeostasis. Here we review recent progresses in this so-called canonical Wnt signaling pathway. We discuss Wnt ligands, agonists and antagonists and their...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861485/ https://ncbi.nlm.nih.gov/pubmed/19619488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.06.016 |
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