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Hippocampal zinc infusion delays the development of afterdischarges and seizures in a kindling model of epilepsy
PURPOSE: Zinc occurs in high concentration in synaptic vesicles of glutamatergic terminals including hippocampal mossy fibers. This vesicular zinc can be synaptically released during neuronal activity, including seizures. Zinc inhibits certain subtypes of N-methyl-D-aspartate (NMDA) and γ-aminobutyr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861481/ https://ncbi.nlm.nih.gov/pubmed/19175668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2008.01913.x |
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