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Hippocampal zinc infusion delays the development of afterdischarges and seizures in a kindling model of epilepsy

PURPOSE: Zinc occurs in high concentration in synaptic vesicles of glutamatergic terminals including hippocampal mossy fibers. This vesicular zinc can be synaptically released during neuronal activity, including seizures. Zinc inhibits certain subtypes of N-methyl-D-aspartate (NMDA) and γ-aminobutyr...

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Bibliografiska uppgifter
Huvudupphovsmän: Elsas, Siegward-M., Hazany, Saman, Gregory, William L., Mody, Istvan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861481/
https://ncbi.nlm.nih.gov/pubmed/19175668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2008.01913.x
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