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Association of Microsatellite Variations of Plasmodium falciparum Na+/H+ Exchanger (Pfnhe-1) Gene with Reduced In Vitro Susceptibility to Quinine: Lack of Confirmation in Clinical Isolates from Africa

We sought to test the association of polymorphisms in Plasmodium falciparum nhe-1 (Pfnhe-1, gene PF13_0019) with in vitro susceptibility to quinine, which was previously reported in a limited number of reference strains or culture-adapted isolates. Determination of in vitro susceptibility to quinine...

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Detalhes bibliográficos
Main Authors: Andriantsoanirina, Valérie, Ménard, Didier, Rabearimanana, Stéphane, Hubert, Véronique, Bouchier, Christiane, Tichit, Magali, Bras, Jacques Le, Durand, Rémy
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861372/
https://ncbi.nlm.nih.gov/pubmed/20439955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2010.09-0327
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