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Protection Against Polyoma Virus-induced Tumors is Perforin-independent

CD8 T cells are necessary for controlling tumors induced by mouse polyoma virus (PyV), but the effector mechanism(s) responsible have not been determined. We examined the PyV tumorigenicity in C57BL/6 mice mutated in Fas, or carrying targeted disruptions in the perforin gene or in both TNF receptor...

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Detalhes bibliográficos
Main Authors: Byers, Anthony M., Hadley, Annette, Lukacher, Aron E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861337/
https://ncbi.nlm.nih.gov/pubmed/17011010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.08.044
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