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A Bayesian Analysis Strategy for Cross-Study Translation of Gene Expression Biomarkers

We describe a strategy for the analysis of experimentally derived gene expression signatures and their translation to human observational data. Sparse multivariate regression models are used to identify expression signature gene sets representing downstream biological pathway events following interv...

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Hlavní autoři: Lucas, Joseph, Carvalho, Carlos, West, Mike
Médium: Artigo
Jazyk:Inglês
Vydáno: Berkeley Electronic Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861325/
https://ncbi.nlm.nih.gov/pubmed/19222378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2202/1544-6115.1436
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