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A Bayesian model for cross-study differential gene expression

In this paper we define a hierarchical Bayesian model for microarray expression data collected from several studies and use it to identify genes that show differential expression between two conditions. Key features include shrinkage across both genes and studies, and flexible modeling that allows f...

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Detalhes bibliográficos
Main Authors: Scharpf, Robert B., Tjelmeland, Håkon, Parmigiani, Giovanni, Nobel, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994029/
https://ncbi.nlm.nih.gov/pubmed/21127725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1198/jasa.2009.ap07611
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