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FOOT-AND-MOUTH DISEASE VIRUS INHIBITION INDUCED IN MICE BY SYNTHETIC DOUBLE-STRANDED RNA (POLYRIBOINOSINIC AND POLYRIBOCYTIDYLIC ACIDS)

Synthetic 2-stranded RNA—a helical complex formed by duplexing homopolymers of polyriboinosinic and polyribocytidylic acids (poly I:C)—induced host resistance to foot-and-mouth disease virus when microgram quantities were injected into mice. There was a graded response as shown by titrations of poly...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Richmond, J. Y., Hamilton, L. D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1969
Fag:
Biological Sciences: Microbiology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286129/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4312754/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.64.1.81
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