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A novel role for 14–3–3σ in regulating epithelial cell polarity

The loss of epithelial polarity is thought to play an important role during mammary tumor progression. Using a unique transgenic mouse model of ErbB2-induced mammary tumorigenesis, we demonstrated previously that amplification of ErbB2 is frequently accompanied by loss of the 14–3–3σ gene. Here, we...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ling, Chen, Zuo, Dongmei, Xue, Bin, Muthuswamy, Senthil, Muller, William J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861193/
https://ncbi.nlm.nih.gov/pubmed/20439433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1896810
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