The Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL) with Everolimus Results in Clinical Responses and Mobilization of CLL Cells into the Circulation

BACKGROUND: Patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) often have chemotherapy resistant disease resulting in a poor prognosis. The aim of this study was to learn if inhibition of the mammalian target of rapamycin (mTOR) would produce tumor respon...

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Main Authors: Zent, Clive S., LaPlant, Betsy R., Johnston, Patrick B., Call, Timothy G., Habermann, Thomas M., Micallef, Ivana N., Witzig, Thomas E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861142/
https://ncbi.nlm.nih.gov/pubmed/20166206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25005
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