Ventilator-Induced Inflammatory Response in Lipopolysaccharide-Exposed Rat Lung Is Mediated by Angiotensin-Converting Enzyme

Angiotensin-converting enzyme (ACE) mediates the ventilator-induced inflammatory response in healthy lungs via angiotensin II (Ang II). A rat model was used to examine the role of ACE and Ang II in the inflammatory response during mechanical ventilation of preinjured (ie, lipopolysaccharide [LPS]-ex...

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Main Authors: Asperen, Roelie M. Wösten-van, Lutter, René, Specht, Patricia A.C., van Woensel, Job B., van der Loos, Chris M., Florquin, Sandrine, Lachmann, Burkhard, Bos, Albert P.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861087/
https://ncbi.nlm.nih.gov/pubmed/20304959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090565
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