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A general electrochemical method for label-free screening of protein–small molecule interactions

Here we report a versatile method by which the interaction between a protein and a small molecule, and the disruption of that interaction by competition with other small molecules, can be monitored electrochemically directly in complex sample matrices.

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Detalhes bibliográficos
Main Authors: Cash, Kevin J., Ricci, Francesco, Plaxco, Kevin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861035/
https://ncbi.nlm.nih.gov/pubmed/19826675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b911558g
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