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Macromolecular scaffolds for immobilizing small molecule microarrays in label-free detection of protein-ligand interactions on solid support

We explored two macromolecular scaffolds, bovine serum albumin (BSA) and polyvinyl alcohol (PVA), as chemically complementary platforms for immobilizing small molecule compounds on functionalized glass slides. We conjugated biotin molecules to BSA and amine-derivatized PVA and subsequently immobiliz...

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Detalhes bibliográficos
Main Authors: Sun, Y. S., Landry, J. P., Fei, Y. Y., Zhu, X. D., Luo, J. T., Wang, X. B., Lam, K. S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751602/
https://ncbi.nlm.nih.gov/pubmed/19563213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac900889p
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