Targeted In Vivo Extracellular Matrix Formation Promotes Neovascularization in a Rodent Model of Myocardial Infarction

BACKGROUND: The extracellular matrix plays an important role in tissue regeneration. We investigated whether extracellular matrix protein fragments could be targeted with antibodies to ischemically injured myocardium to promote angiogenesis and myocardial repair. METHODOLOGY/PRINCIPAL FINDINGS: Four...

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Main Authors: Mihardja, Shirley S., Gao, Dongwei, Sievers, Richard E., Fang, Qizhi, Feng, Jinjin, Wang, Jianming, Vanbrocklin, Henry F., Larrick, James W., Huang, Manley, Dae, Michael, Lee, Randall J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860995/
https://ncbi.nlm.nih.gov/pubmed/20442783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010384
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