Targeted In Vivo Extracellular Matrix Formation Promotes Neovascularization in a Rodent Model of Myocardial Infarction

BACKGROUND: The extracellular matrix plays an important role in tissue regeneration. We investigated whether extracellular matrix protein fragments could be targeted with antibodies to ischemically injured myocardium to promote angiogenesis and myocardial repair. METHODOLOGY/PRINCIPAL FINDINGS: Four...

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Detalhes bibliográficos
Main Authors: Mihardja, Shirley S., Gao, Dongwei, Sievers, Richard E., Fang, Qizhi, Feng, Jinjin, Wang, Jianming, Vanbrocklin, Henry F., Larrick, James W., Huang, Manley, Dae, Michael, Lee, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860995/
https://ncbi.nlm.nih.gov/pubmed/20442783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010384
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