Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development

The lymphatic system plays a key role in tissue fluid homeostasis. Lymphatic dysfunction contributes to the pathogenesis of many human diseases, including lymphedema and tumor metastasis. However, the mechanisms regulating lymphangiogenesis remain largely unknown. Here, we show that COUP-TFII (also...

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Detaylı Bibliyografya
Asıl Yazarlar: Lin, Fu-Jung, Chen, Xinpu, Qin, Jun, Hong, Young-Kwon, Tsai, Ming-Jer, Tsai, Sophia Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860940/
https://ncbi.nlm.nih.gov/pubmed/20364082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40101
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