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Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development

The lymphatic system plays a key role in tissue fluid homeostasis. Lymphatic dysfunction contributes to the pathogenesis of many human diseases, including lymphedema and tumor metastasis. However, the mechanisms regulating lymphangiogenesis remain largely unknown. Here, we show that COUP-TFII (also...

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Detalhes bibliográficos
Main Authors: Lin, Fu-Jung, Chen, Xinpu, Qin, Jun, Hong, Young-Kwon, Tsai, Ming-Jer, Tsai, Sophia Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860940/
https://ncbi.nlm.nih.gov/pubmed/20364082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40101
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