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Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia

Sepsis is associated with a systemic activation of coagulation and an excessive inflammatory response. Anticoagulants have been shown to inhibit both coagulation and inflammation in sepsis. In this study, we used both genetic and pharmacologic approaches to analyze the role of tissue factor and prot...

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Bibliografische gegevens
Hoofdauteurs: Pawlinski, Rafal, Pedersen, Brian, Schabbauer, Gernot, Tencati, Michael, Holscher, Todd, Boisvert, William, Andrade-Gordon, Patricia, Frank, Rolf Dario, Mackman, Nigel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860856/
https://ncbi.nlm.nih.gov/pubmed/14576054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-09-3051
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