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Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia

Sepsis is associated with a systemic activation of coagulation and an excessive inflammatory response. Anticoagulants have been shown to inhibit both coagulation and inflammation in sepsis. In this study, we used both genetic and pharmacologic approaches to analyze the role of tissue factor and prot...

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Detalhes bibliográficos
Main Authors: Pawlinski, Rafal, Pedersen, Brian, Schabbauer, Gernot, Tencati, Michael, Holscher, Todd, Boisvert, William, Andrade-Gordon, Patricia, Frank, Rolf Dario, Mackman, Nigel
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860856/
https://ncbi.nlm.nih.gov/pubmed/14576054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-09-3051
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