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Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia

Sepsis is associated with a systemic activation of coagulation and an excessive inflammatory response. Anticoagulants have been shown to inhibit both coagulation and inflammation in sepsis. In this study, we used both genetic and pharmacologic approaches to analyze the role of tissue factor and prot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pawlinski, Rafal, Pedersen, Brian, Schabbauer, Gernot, Tencati, Michael, Holscher, Todd, Boisvert, William, Andrade-Gordon, Patricia, Frank, Rolf Dario, Mackman, Nigel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860856/
https://ncbi.nlm.nih.gov/pubmed/14576054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-09-3051
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