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Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation

Eleven authenticated botanicals used in the traditional Chinese medicine Huo-Luo-Xiao-Ling Dan were screened for ligands to cyclooxygenase (COX) using pulsed ultrafiltration liquid chromatography-mass spectrometry, and a mass spectrometry-based enzyme assay was used to determine the concentration of...

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Detalhes bibliográficos
Main Authors: Cao, Hongmei, Yu, Rui, Choi, Yongsoo, Ma, Zhong-Ze, Zhang, Hongjie, Xiang, Wei, Lee, David Yue-Wei, Berman, Brian M., Moudgil, Kamal D, Fong, Harry H.S., van Breemen, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860736/
https://ncbi.nlm.nih.gov/pubmed/20188172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2010.02.007
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