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Anti-AIDS Agents 81. Design, Synthesis and Structure-Activity Relationship Study of Betulinic Acid and Moronic Acid Derivatives as Potent HIV Maturation Inhibitors

In our continuing study of triterpene derivatives as potent anti-HIV agents, different C-3 conformationally restricted betulinic acid (BA, 1) derivatives were designed and synthesized in order to explore the conformational space of the C-3 pharmacophore. 3-O-Monomethylsuccinyl- betulinic acid (MSB)...

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書誌詳細
主要な著者: Qian, Keduo, Kuo, Reen-Yun, Chen, Chin-Ho, Huang, Li, Morris-Natschke, Susan L., Lee, Kuo-Hsiung
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860721/
https://ncbi.nlm.nih.gov/pubmed/20329730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901782m
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