HIV-1 viral protein r induces ERK and caspase-8 dependent apoptosis in renal tubular epithelial cells

OBJECTIVE: HIV-associated nephropathy is the most common cause of end stage renal disease in persons with HIV/AIDS and is characterized by focal glomerulosclerosis and dysregulated renal tubular epithelial cell (RTEC) proliferation and apoptosis. HIV-1 viral protein r (Vpr) has been implicated in HI...

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Bibliografiske detaljer
Main Authors: Snyder, Alexandra, Alsauskas, Zygimantas C., Leventhal, Jeremy S., Rosenstiel, Paul E., Gong, Pengfei, Chan, Justin JK, Barley, Kevin, He, John C., Klotman, Mary E., Ross, Michael J., Klotman, Paul E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860650/
https://ncbi.nlm.nih.gov/pubmed/20404718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e328337b0ab
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