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Genomic imprinting—an epigenetic gene-regulatory model

Epigenetic mechanisms (Box 1) are considered to play major gene-regulatory roles in development, differentiation and disease. However, the relative importance of epigenetics in defining the mammalian transcriptome in normal and disease states is unknown. The mammalian genome contains only a few mode...

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Detalhes bibliográficos
Main Authors: Koerner, Martha V, Barlow, Denise P
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860637/
https://ncbi.nlm.nih.gov/pubmed/20153958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2010.01.009
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