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Mechanisms and inhibition of HIV integration

HIV integrase is required for viral replication and a rationale target for antiretroviral therapies. Integrase inhibitors are potentially complementary to current treatments. This review focuses on the mechanisms of HIV integration. The roles of viral and cellular co-factors during pre-integration c...

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Detalhes bibliográficos
Main Authors: Marchand, Christophe, Johnson, Allison A, Semenova, Elena, Pommier, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860614/
https://ncbi.nlm.nih.gov/pubmed/20431697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddmec.2006.05.004
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