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Allosteric mechanism of Ca(2+) activation and H(+)-inhibited gating of the MthK K(+) channel
MthK is a Ca(2+)-gated K(+) channel whose activity is inhibited by cytoplasmic H(+). To determine possible mechanisms underlying the channel’s proton sensitivity and the relation between H(+) inhibition and Ca(2+)-dependent gating, we recorded current through MthK channels incorporated into planar l...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860591/ https://ncbi.nlm.nih.gov/pubmed/20421375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910387 |
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