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Surpassing Specificity Limits of Nucleic Acid Probes via Cooperativity

The failure to correctly identify single nucleotide polymorphisms (SNPs) significantly contributes to the misdiagnosis of infectious disease. Contrary to the strategy of creating shorter probes to improve SNP differentiation, we created larger probes that appeared to increase selectivity. Specifical...

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Bibliografski detalji
Glavni autori: Satterfield, Brent C., Bartosiewicz, Matt, West, Jay A.A., Caplan, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860473/
https://ncbi.nlm.nih.gov/pubmed/20304941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2010.090056
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