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Surpassing Specificity Limits of Nucleic Acid Probes via Cooperativity
The failure to correctly identify single nucleotide polymorphisms (SNPs) significantly contributes to the misdiagnosis of infectious disease. Contrary to the strategy of creating shorter probes to improve SNP differentiation, we created larger probes that appeared to increase selectivity. Specifical...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Investigative Pathology
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860473/ https://ncbi.nlm.nih.gov/pubmed/20304941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2010.090056 |
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