A Commercial Real-Time PCR Kit Provides Greater Sensitivity than Direct Sequencing to Detect KRAS Mutations: A Morphology-Based Approach in Colorectal Carcinoma

KRAS mutation testing has become a standard procedure in the management of patients with carcinomas. The most frequently used method for KRAS testing is direct sequencing of PCR products. The development of commercial real-time quantitative PCR kits offers a useful alternative since they are in theo...

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Detalhes bibliográficos
Main Authors: Angulo, Bárbara, García-García, Elena, Martínez, Rebeca, Suárez-Gauthier, Ana, Conde, Esther, Hidalgo, Manuel, López-Ríos, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860464/
https://ncbi.nlm.nih.gov/pubmed/20203003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2010.090139
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