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Conformational Preferences of a 14-Residue Fibrillogenic Peptide from Acetylcholinesterase

[Image: see text] A 14-residue fragment from near the C-terminus of the enzyme acetylcholinesterase (AChE) is believed to have a neurotoxic/neurotrophic effect acting via an unknown pathway. While the peptide is α-helical in the full-length enzyme, the structure and association mechanism of the frag...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vijayan, Ranjit, Biggin, Philip C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2010
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860372/
https://ncbi.nlm.nih.gov/pubmed/20356043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1001807
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