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A Steroid in a Lipid Bilayer: Localization, Orientation, and Energetics

Steroid hormones are known to freely partition into lipid bilayers. As a case study, we investigated the behavior of the steroid hormone cortisone in a model lipid bilayer. First, we looked at energy barriers involved in the partitioning of a single molecule into a bilayer using umbrella sampling mo...

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Bibliographic Details
Main Authors: Vijayan, Ranjit, Biggin, Philip C.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547426/
https://ncbi.nlm.nih.gov/pubmed/18689457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.140087
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