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Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes

The ENU-induced repro8 mutation was identified in a screen to uncover genes that control mouse gametogenesis. repro8 causes male-limited infertility, with failure of spermatocytes to exit meiotic prophase via the G2/MI transition. The repro8 mutation is in the Eif4g3 gene, encoding eukaryotic transl...

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Bibliografske podrobnosti
Main Authors: Sun, Fengyun, Palmer, Kristina, Handel, Mary Ann
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860251/
https://ncbi.nlm.nih.gov/pubmed/20430745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.043125
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