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Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes
The ENU-induced repro8 mutation was identified in a screen to uncover genes that control mouse gametogenesis. repro8 causes male-limited infertility, with failure of spermatocytes to exit meiotic prophase via the G2/MI transition. The repro8 mutation is in the Eif4g3 gene, encoding eukaryotic transl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860251/ https://ncbi.nlm.nih.gov/pubmed/20430745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.043125 |
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