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Estimation of Genotype Relative Risks From Pedigree Data by Retrospective Likelihoods

Pedigrees collected for linkage studies are a valuable resource that could be used to estimate genetic relative risks (RRs) for genetic variants recently discovered in case-control genome wide association studies. To estimate RRs from highly ascertained pedigrees, a pedigree “retrospective likelihoo...

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Hlavní autoři: Schaid, Daniel J., McDonnell, Shannon K., Riska, Shaun M., Carlson, Erin E., Thibodeau, Stephen N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860197/
https://ncbi.nlm.nih.gov/pubmed/20039378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20460
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