Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome

Structural variation (SV) is a rich source of genetic diversity in mammals, but due to the challenges associated with mapping SV in complex genomes, basic questions regarding their genomic distribution and mechanistic origins remain unanswered. We have developed an algorithm (HYDRA) to localize SV b...

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Detalhes bibliográficos
Main Authors: Quinlan, Aaron R., Clark, Royden A., Sokolova, Svetlana, Leibowitz, Mitchell L., Zhang, Yujun, Hurles, Matthew E., Mell, Joshua C., Hall, Ira M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860164/
https://ncbi.nlm.nih.gov/pubmed/20308636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.102970.109
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