Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers

Clustering of multiple transcription factor binding sites (TFBSs) for the same transcription factor (TF) is a common feature of cis-regulatory modules in invertebrate animals, but the occurrence of such homotypic clusters of TFBSs (HCTs) in the human genome has remained largely unknown. To explore w...

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Detalhes bibliográficos
Principais autores: Gotea, Valer, Visel, Axel, Westlund, John M., Nobrega, Marcelo A., Pennacchio, Len A., Ovcharenko, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860159/
https://ncbi.nlm.nih.gov/pubmed/20363979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.104471.109
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