A Variance-Component Framework for Pedigree Analysis of Continuous and Categorical Outcomes

Variance-component methods are popular and flexible analytic tools for elucidating the genetic mechanisms of complex quantitative traits from pedigree data. However, variance-component methods typically assume that the trait of interest follows a multivariate normal distribution within a pedigree. S...

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Bibliografiske detaljer
Main Authors: Epstein, Michael P., Hunter, Jessica E., Allen, Emily G., Sherman, Stephanie L., Lin, Xihong, Boehnke, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860148/
https://ncbi.nlm.nih.gov/pubmed/20436936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12561-009-9010-5
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