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Molecular determinants of the antitumor effects of trichostatin A in pancreatic cancer cells

AIM: To gain molecular insights into the action of the histone deacetylase inhibitor (HDACI) trichostatin-A (TSA) in pancreatic cancer (PC) cells. METHODS: Three PC cell lines, BxPC-3, AsPC-1 and CAPAN-1, were treated with various concentrations of TSA for defined periods of time. DNA synthesis was...

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Detalhes bibliográficos
Main Authors: Emonds, Elisabeth, Fitzner, Brit, Jaster, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860073/
https://ncbi.nlm.nih.gov/pubmed/20419833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i16.1970
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