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Zinc Mesoporphyrin Induces Rapid Proteasomal Degradation of Hepatitis C Nonstructural 5A Protein in Human Hepatoma Cells

BACKGROUND & AIMS: The nonstructural 5A (NS5A) protein of hepatitis C virus (HCV), plays a critical role in HCV replication and is an attractive target for the therapy of HCV infection. So far, little is known about the post-translational regulation of NS5A protein and its precise role in HCV RN...

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Bibliografski detalji
Glavni autori: Hou, Weihong, Tian, Qing, Zheng, Jianyu, Bonkovsky, Herbert L.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860067/
https://ncbi.nlm.nih.gov/pubmed/19909748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.11.001
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