The Attenuation of Central Angiotensin II-dependent Pressor Response and Intra-neuronal Signaling by Intracarotid Injection of Nanoformulated Copper/Zinc Superoxide Dismutase

Adenoviral-mediated overexpression of the intracellular superoxide (O(2)(•−)) scavenging enzyme copper/zinc superoxide dismutase (CuZnSOD) in the brain attenuates central angiotensin II (AngII)-induced cardiovascular responses. However, the therapeutic potential for adenoviral vectors is weakened by...

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Hlavní autoři: Rosenbaugh, Erin G., Roat, James, Gao, Lie, Yang, Rui-Fang, Manickam, Devika S., Yin, Jing-Xiang, Schultz, Harold D., Bronich, Tatiana K., Batrakova, Elena V., Kabanov, Alexander V., Zucker, Irving H., Zimmerman, Matthew C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860066/
https://ncbi.nlm.nih.gov/pubmed/20378166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.03.026
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