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Connective Tissue Growth Factor Promotes Fibrosis Downstream of TGFβ and IL-6 in Chronic Cardiac Allograft Rejection

Cardiac transplantation is an effective treatment for multiple types of heart failure refractive to therapy. Although immunosuppressive therapeutics have increased survival rates within the first year post-transplant, chronic rejection (CR) remains a significant barrier to long term graft survival....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Booth, A. J., Csencsits-Smith, K., Wood, S. C., Lu, G., Lipson, K. E., Bishop, D. K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860022/
https://ncbi.nlm.nih.gov/pubmed/19788504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2009.02826.x
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