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Immuno-regulatory function of IL-27 and TGFβ1 in cardiac allograft transplantation.

BACKGROUND: Deciphering the mechanisms of tolerance represents a crucial aim of research in transplantation. We previously identified by DNA chip, IL-27 p28 and TGFβ1, as over-expressed in a model of rat cardiac allograft tolerance mediated by regulatory CD4(+)CD25(+) T cells. The role of these two...

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Detalhes bibliográficos
Main Authors: Le Texier, Laetitia, Thebault, Pamela, Carvalho-Gaspar, Manuela, Vignard, Virginie, Merieau, Emmanuel, Usal, Claire, Cuturi, Maria-Cristina, Wood, Kathryn J, Chiffoleau, Elise
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442234/
https://ncbi.nlm.nih.gov/pubmed/22790384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31825b0c38
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