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ICOS expression by effector T cells influences the ability of regulatory T cells to inhibit anti-chromatin B cell responses in recipient mice

T regulatory cells are critical for the prevention of autoimmunity. Specifically, Treg cells can control anti-chromatin antibody production in vivo, and this correlates with decreased ICOS expression on CD4(+) T helper cells. Here we test the significance of high ICOS expression by T effector cells,...

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Detalhes bibliográficos
Main Authors: Hondowicz, Brian D., Batheja, Amrita O., Metzgar, Michele H., Caton, Andrew J., Erikson, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859982/
https://ncbi.nlm.nih.gov/pubmed/20022728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2009.11.016
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