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Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes
Repeated administration of MDMA (ecstasy) produces eccentric left ventricular (LV) dilation and diastolic dysfunction. While the mechanism(s) underlying this toxicity are unknown; oxidative stress plays an important role. MDMA is metabolized into redox cycling metabolites that produce superoxide. In...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859611/ https://ncbi.nlm.nih.gov/pubmed/19333788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12012-009-9034-6 |
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