Trypanosoma cruzi Subverts Host Cell Sialylation and May Compromise Antigen-specific CD8(+) T Cell Responses

Upon activation, cytotoxic CD8(+) T lymphocytes are desialylated exposing β-galactose residues in a physiological change that enhances their effector activity and that can be monitored on the basis of increased binding of the lectin peanut agglutinin. Herein, we investigated the impact of sialylatio...

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Bibliographische Detailangaben
Hauptverfasser: Freire-de-Lima, Leonardo, Alisson-Silva, Frederico, Carvalho, Sebastião T., Takiya, Christina M., Rodrigues, Maurício M., DosReis, George A., Mendonça-Previato, Lucia, Previato, José O., Todeschini, Adriane R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859498/
https://ncbi.nlm.nih.gov/pubmed/20106975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.096305
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