Evolution of T-cell clonality in a patient with Ph-negative acute lymphocytic leukemia occurring after interferon and imatinib therapy for Ph-positive chronic myeloid leukemia

INTRODUCTION: The development of Philadelphia chromosome (Ph) negative acute leukemia/myelodysplastic syndrome (MDS) in patients with Ph-positive chronic myeloid leukemia (CML) is very rare. The features of restrictive usage and absence of partial T cell clones have been found in patients with CML....

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Hauptverfasser: Wang, Liang, Zhu, Kanger, Zha, Xianfeng, Chen, Shaohua, Yang, Lijian, Chen, Si, Li, Yangqiu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859394/
https://ncbi.nlm.nih.gov/pubmed/20377918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-3-14
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