INHIBITION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE BY THE LIPID PHOSPHATASE PTEN

PTEN (phosphatase and tensin homologue deleted on chromosome 10) is a lipid phosphatase that functions as a negative regulator of the phosphoinositide-3-kinase (PI3K) pathway. The present study sought to examine in depth the interaction between PTEN and eNOS activity. Co-expression of eNOS and PTEN...

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Detalhes bibliográficos
Main Authors: Church, Jarrod E., Qian, Jin, Kumar, Sanjiv, Black, Stephen M., Venema, Richard C., Papapetropoulos, Andreas, Fulton, David J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859103/
https://ncbi.nlm.nih.gov/pubmed/19962452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2009.11.007
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