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Acetylation of WRN Protein Regulates Its Stability by Inhibiting Ubiquitination

BACKGROUND: WRN is a multi-functional protein involving DNA replication, recombination and repair. WRN acetylation has been demonstrated playing an important role in response to DNA damage. We previously found that WRN acetylation can regulate its enzymatic activities and nuclear distribution. METHO...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Kai, Wang, Rui, Lozada, Enerlyn, Fan, Wei, Orren, David K., Luo, Jianyuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859066/
https://ncbi.nlm.nih.gov/pubmed/20428248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010341
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