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Analysis of Single Nucleotide Polymorphisms (SNPs) of the small-conductance calcium activated potassium channel (SK3) gene as genetic modifier of the cardiac phenotype in myotonic dystrophy type 1 patients

Myotonic dystrophy type 1 (DM1) is the most frequently inherited neuromuscular disease in adults. It is a multisystemic disorder with major cardiac involvement most commonly represented by first-degree atrioventricular heart block (AVB), followed by different degrees of bundle-branch and intraventri...

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Autors principals: Rinaldi, F, Botta, A, Vallo, L, Contino, G, Morgante, A, Iraci, R, Catalli, C, Silvestri, G, Ventriglia, VM, Politano, L, Novelli, G
Format: Artigo
Idioma:Inglês
Publicat: Pacini Editore SpA 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858941/
https://ncbi.nlm.nih.gov/pubmed/19472917
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