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Signaling through the A2B Adenosine Receptor Dampens Endotoxin-Induced Acute Lung Injury

Sepsis and septic acute lung injury are among the leading causes for morbidity and mortality of critical illness. Extracellular adenosine is a signaling molecule implicated in the cellular adaptation to hypoxia, ischemia or inflammation. Therefore, we pursued the role of the A2B adenosine receptor (...

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Hlavní autoři: Schingnitz, Ulrich, Hartman, Katherine, MacManus, Christopher F., Eckle, Tobias, Zug, Stephanie, Colgan, Sean P., Eltzschig, Holger K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858788/
https://ncbi.nlm.nih.gov/pubmed/20348420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903035
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